Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE268367 Altered Monocyte Inflammatory Program and Ontogeny Mediate Enhanced Lung Injury in Sepsis Survivors [RNA-Seq] May 25, 2026
  Contributors : Scott J Denstaedt ; Breanna McBean ; Alan P Boyle ; Brett Arenberg ; Matthias Mack ; Bethany B Moore ; Michael W Newstead ; Benjamin H Singer ; Jennifer Cano ; Hallie C Prescott ; Helen S Goodridge ; Rachel L ZemansSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPersistent inflammation after sepsis is ass […]
• GSE83224 Transcriptional Regulatory Networks Involved in Melanogenesis Uncovered by Chemo-genomic Profiling May 25, 2026
  Contributors : Krishnamurthy Natarajan ; Kritika KirtySeries Type : Expression profiling by arrayOrganism : Mus musculusThis study was aimed to identify genome-wide changes in the transcriptome profile of mouse B16-F10 melanoma cells undergoing melanogenesis. The pigmentation state of the B16 cells could be controlled depending on the media conditions. We in […]
• GSE296772 Assessment of the Health Effects of Phytopharmaceuticals Used in Potato Cultivation [Brain] May 25, 2026
  Contributors : Anca Lucau-Danila ; Sandy Theysgeur ; Camille Dugardin ; Sebastien LemièreSeries Type : Expression profiling by arrayOrganism : Mus musculusPotatoes are one of the most widely consumed staple foods globally, yet their cultivation and storage often involve the use of multiple phytopharmaceutical products, raising concerns about potential health […]
• GSE296688 Assessment of the Health Effects of Phytopharmaceuticals Used in Potato Cultivation [Jejunum] May 25, 2026
  Contributors : Anca Lucau-Danila ; Sandy Theysgeur ; Camille Dugardin ; Sebastien LemièreSeries Type : Expression profiling by arrayOrganism : Mus musculusPotatoes are one of the most widely consumed staple foods globally, yet their cultivation and storage often involve the use of multiple phytopharmaceutical products, raising concerns about potential health […]
• GSE303202 Hypotensive major health effect of Ziziphus jujuba highlighted by nutrigenomic and cardiovascular studies May 25, 2026
  Contributors : Anca Lucau-Danila ; Abderrahim Ziyyat ; Sevser SahpazSeries Type : Expression profiling by arrayOrganism : Mus musculusTo evaluate the antihypertensive effect of Ziziphus jujuba (Zi), we conducted a nutrigenomic analysis to examine the changes induced by the administration of the aqueous extracts of these plants on gene expression in mice. Car […]
• GSE297912 Development of an AI Model to Predict Tumor Immune Responsiveness in Colorectal Cancer Using Organoid–Immune Co-Culture platforms May 25, 2026
  Contributors : Misun Park ; Jiyeon Kim ; Jinguen Rheey ; Jihwan Park ; Ji-yeon ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to functionally assess tumor immune responsiveness in colorectal cancer using a co-culture platform combining patient-derived organoids (PDOs) with autologous tumor-reactive […]
• GSE331524 Transcriptomic analysis of hippocampus and prefrontal cortex in a mouse model of chronic radiation-induced gastrointestinal injury May 25, 2026
  Contributors : Hyosun Jang ; Yeonghoon Son ; Hae-June LeeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic radiation-induced gastrointestinal injury is associated with persistent gut dysfunction and microbiome alterations, which may contribute to extra-intestinal complications including neurovascular and behaviora […]
• GSE310741 Characterizing breast cancer cell biochemical responses to fluid shear in a 3D loading model May 25, 2026
  Contributors : Shreya Venkatesh ; Andrea Ordonez ; William R Thompson ; Edward B Chuong ; Maureen E LynchSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBone is the most common site of breast cancer metastasis—only 12% of patients with skeletal metastases demonstrate a 5-year survival rate after diagnosis. Bone metastas […]
• GSE331535 TOR-dependent transcriptome responses to water deficit in Arabidopsis seedlings May 25, 2026
  Contributors : Dhriti Singh ; Ashverya LaxmiSeries Type : Expression profiling by arrayOrganism : Arabidopsis ; Arabidopsis thalianaTo assess the role of TOR kinase, Col-0 and TOR RNAi (tori 35-7) seedlings were subjected to water-deficit treatment and analyzed using Affymetrix microarrays.Comparative transcriptome profiling of Col-0 and TOR RNAi seedlings w […]
• GSE331532 Identification and Characterization of MicroRNAs in female 0edaleus asiaticus(Orthoptera:Oedipodidae) May 25, 2026
  Contributors : Shuangshuang Ge ; Shujing GAOSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Oedaleus asiaticusOedaleus asiaticus is a dominant grasshopper in northern China’s grasslands and agro-pastoral zones, yet its growth and development miRNA regulation remains poorly understood. Here, we performed small RNA sequencing on […]
• GSE331537 Transcriptomic analysis of two rice varieties, QJ and LJ, with differential responses to bicarbonate-induced salt-alkali stress. May 25, 2026
  Contributors : Bo Qin ; Tie Li ; Minglong Sun ; Yuanling Zhao ; Dongmei LiSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza sativaThis study aimed to elucidate the molecular mechanisms underlying the response to salt‑alkali stress by analyzing transcriptomic changes in two rice varieties, QJ and LJ, which exhibit differential r […]
• GSE332556 Tumor-associated Macrophage GnT-V Enhances Sensitivity to Antitumor Immunotherapy through Branched N-Glycosylation to Promote M1 Polarization May 25, 2026
  Contributor : Depeng YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor tissues with differential sensitivity to immunotherapy were sequenced using The DNBelab C4 /DNBelab TaiM4 Series Single-Cell Library Prep Set (MGI) was used for sequencing and sequenced on the DNBSEQ-T7 sequencer with pair-end sequencing. Imm […]
• GSE332566 Study of the predictive value of genomic, transcriptomic and epigenetic biomarkers in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with PD-1/PD-L1 inhibitors May 25, 2026
  Series Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensImmune checkpoint inhibitors have improved survival in several solid tumors, including head and neck squamous cell carcinoma (HNSCC). However, current use of PD-1/PD-L1 inhibitors relies on PD-L1 expression, which does not reliably predict patient response. Therefore, better pre […]
• GSE332631 Expression profile of Mgat5 knockout (CRISPR-Cas9) in murine colon adenocarcinoma cells (MC38) May 25, 2026
  Contributors : Michelle de-Souza-Ferreira ; Eliana Abdelhay ; Renata Binato ; Julio Cesar Madureira de Freitas JuniorSeries Type : Expression profiling by arrayOrganism : Mus musculusmRNA samples from murine colon adenocarcinoma cells (MC38) (Control condition MC38 WT; Empty vector condition MC38 MOCK; Knockout condition 1: MC38 KO T5 clone 1 and Knockout co […]
• GSE331507 Multi-omics profiling of glioma cells treated with I-BRD9 May 25, 2026
  Contributors : Yuanlang Hu ; Kang Ouyang ; Jiayi Lyu ; Chunyu CaoSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensBRD9 is a glioma-associated epigenetic regulator. This study profiles transcriptomic and chromatin-level changes in glioma cells after I-BRD9 […]