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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294344 DEAH-BOX HELICASE 8 IS A REGULATOR OF HEAT SHOCK FACTOR 1 February 17, 2026Contributors : Jennifer R Tall ; Alexandra Vasile ; Pradeep Ramagiri ; James Campbell ; Caitlin Davies ; Marissa Powers ; Toby Roe ; Deivendran Sankaran ; Hannah Wang ; Konstantinos Mitsopoulos ; Bissan Al-Lazikani ; Robert V Montfort ; Emmanuel D Billy ; Paul Workman ; Paul A ClarkeSeries Type : Expression profiling by high throughput sequencingOrganism : H […]
- GSE292263 Effect of hypoxia on murine splenic NK cells February 17, 2026Contributors : Sebastiano Giorgetta ; Ana Stojanovic ; Cerwenka AdelheidSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNK cells responses can be significantly affected by microenvironmental conditions. In pathological conditions, oxygen concentration in tissues can be reduced, lading to hypoxia. Here, we investigated h […]
- GSE278725 LARP6 shapes the mRNA translation of fibrogenic genes [eCLIP] February 17, 2026Contributors : Hyun Y Kim ; Wonseok Lee ; Sara B Rosenthal ; Cuijuan Han ; Brian A Yee ; Steven M Blue ; Jesiel Diaz ; Jyotiprakash Jonnalagadda ; Kanani Hokutan ; Haeum Jang ; Chen-Ting Ma ; Andrey Bobkov ; Eduard Sergienko ; Michael Jackson ; Branko Stefanovic ; Tatiana Kisseleva ; Orel Mizrahi ; Gene W Yeo ; David A BrennerSeries Type : Expression profili […]
- GSE231768 Vitamin D binding protein induces skeletal muscle atrophy and contributes to cancer-associated muscle wasting independently of vitamin D status February 17, 2026Contributors : Tommaso Raiteri ; Andrea Scircoli ; Simone Reano ; Stefania Faletti ; Francesco Favero ; Giuliana Pelicci ; Davide Corà ; Nicoletta FilighedduSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe evaluated the modulation of mRNA in gastrocenmii of wild type and Gc-KO C57BL/6 mice upon cachexia induction with […]
- GSE285229 Understanding the effect of milk fat containing diet in the gut epithelial homeostasis. February 17, 2026Contributors : Chen Chongtham ; Raunak Kar ; Dr Veena S Patil ; Dr G Aneeshkumar ArimbasseriSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe employed single-cell RNA sequencing using 10X Genomics technology to investigate the effect of milk fat diet on gut homeostasis. We have observed that mice with dextran sodium su […]
- GSE281196 An immunobiliary single-cell atlas resolves crosstalk between type 2 conventional dendritic cells and γδ T cells in cholangitis [Multiome] February 17, 2026Contributors : Stefan Thomann ; Dominic GrünSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Mus musculusThe liver biliary niche serves as a reservoir of tissue-resident immune cells and supports tissue fibrosis upon damage, yet the role of peribiliary immune cells d […]
- GSE319431 RNA-seq of Human nasopharyngeal carcinoma cells in BALF2-LR and BALF2-HR overexpress group February 17, 2026Contributor : Wei XiongSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the biological function of EBV BALF2-HR in NPC pathogenesis, we constructed overexpression vectors for BALF2-HR and BALF2-LR (used as a control) and transfected them into the EBV-negative NPC cell line HK1 [Fig. S1D]. Differential gene […]
- GSE286290 Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders [CUT&RUN] February 17, 2026Contributors : Rodrigo Lucena Borges ; Gretter Gonzalez ; Harikumar Arigela ; Yingyu Huang ; Lucas D Caeiro ; Nikolai Fattakhov ; Stefano Lepore ; Liliana Garcia-Martinez ; Matea Maurice ; Pushti D Mehta ; Emily J Park ; Kailynn MacGillivray ; Jevithen Nehru ; Matthew Chau ; Maria C Robayo2 ; Clemer Abad ; Alicia Bilbao-Martinez ; Fabiola Monteiro ; Xi Luo ; […]
- GSE319500 Predictability of progression free survival in ovarian cancer February 17, 2026Contributors : Lucy B Kleunen ; Grace Bowman ; Sarah E Stockman ; Logan Barrios ; Hope A Townsend ; Kimberly R Jordan ; Rebecca J Wolsky ; Kian Behbakht ; Matthew J Sikora ; Benjamin G Bitler ; Aaron ClausetSeries Type : Expression profiling by arrayOrganism : Homo sapiensGiven the interrelated mechanisms by which changes to the tumor microenvironment (TME) […]
- GSE319460 Transcriptomic Profiling on Intestine of Diabetic and Septic Mice [miRNA-seq] February 17, 2026Contributors : Xinjin Chi ; Fang Tan ; Lei ZhengSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusSepsis is a severe clinical syndrome related to an exaggerated host immune response to infection as well as systematic inflammation and serious tissue damage. Sepsis-induced intestine injury is one of the most frequent an […]
- GSE319560 The transcriptional repressor Ssn6 modulates phase separation to regulate fungal gene expression February 17, 2026Contributors : Maureen A Dowell ; Mae I Staples ; Corey Frazer ; Richard J BennettSeries Type : Expression profiling by high throughput sequencingOrganism : Candida albicansThe transcriptional regulation of cell fate plays a central role in eukaryotic cell differentiation. In the human fungal pathogen Candida albicans, the white-to-opaque switch is controlle […]
- GSE319636 Viral Mimicry may Help Explain Immunogenic Cell Death February 17, 2026Contributors : Matthew S Levine ; Jiexi Li ; Lauren I R Ehrlich ; Ronald A DePinho ; Brent Iverson ; Jonathan L SesslerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusViral mimicry may be an underappreciated contributor to chemotherapeutic potency in animal models and patients. This hypothesis is based on studies of a b […]
- GSE319696 Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing [MEF_RNAseq] February 17, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome has been controversial over the last 15 years, and the functional role of H3K9 methylation in X chromosome inactivation in any species has remained largely unexplored. Here we report t […]
- GSE289831 Splenic nerves NE-β2AR axis exacerbate septic acute kidney injury via modulating neutrophilic immunosuppression [scRNA-seq] February 17, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSepsis is characterized by chronic inflammation and immunosuppression, two immune states that hinder effective infection control and significantly contribute to renal pathological damage. Recent studies have underscored the crucial role of splenic neuroimmune interactions […]
- GSE319215 Monocytes defined by platelet interactions and oxidative stress signaling underlie HIV-associated atherosclerosis February 17, 2026Contributors : Ruoqiao Wang ; Zachary Boodoo ; Karli Sutton ; Jun-ichi Abe ; Sanjay B Maggirwa ; Giovanni Schifitto ; Meera V Singh ; Juilee ThakarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBackground: Monocytes contribute to atherosclerosis (AS) by migrating into inflamed endothelium and differentiating into foam […]