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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE223225 Identification and characterization of functional long noncoding RNAs in human fibroblast aging January 17, 2026Contributors : Xiaojuan Teng ; Jiajian ZhouSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe sought to validate the function of PURPL using gain of function and loss of function assay during BJ cells senescence.
- GSE287261 Longitudinal Methylomic changes in PTSD following Sub-Anaesthetic Oral Ketamine Administration January 17, 2026Contributor : Nathan WellingtonSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensThis study is part of an investigation into the differential gene expression and methylation patterns in response to sub-anaesthetic oral ketamine treatment of PTSD to identify key molecular markers in building a predictive profile in determining l […]
- GSE282108 Genetically encoded fluorescent reporters to visualize Lewy pathology in live brain January 17, 2026Contributors : Li Zhang ; Qian Wu ; Xiaoqun Wang ; Peng CaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusLewy bodies, a pathological hallmark of Parkinson’s disease, are α-synuclein-enriched cytoplasmic inclusions that drive progressive neurodegeneration these reporters provide an opportunity to directly visualize α-s […]
- GSE287869 Targeted citrullination enables p53 binding to non-canonical sites [163] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE287470 Disease Associated Microglial TLR4-Lyn kinase is a critical regulator of neuroinflammation, Aβ phagocytosis, neuronal damage and cell survival in a 5XFAD mouse model. January 17, 2026Contributors : Rezwanul Islam ; Khalid HanafySeries Type : OtherOrganism : Mus musculusDisease-Associated Microglia (DAM) are a focus in Alzheimer's disease (AD) research due to their central involvement in the response to amyloid-beta plaques. Microglial Toll-like receptor 4 (TLR4) is instrumental in the binding of fibrillary amyloid proteins, while Ly […]
- GSE287871 Targeted citrullination enables p53 binding to non-canonical sites [165] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Activation of p53 […]
- GSE287870 Targeted citrullination enables p53 binding to non-canonical sites [164] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Activation of p53 […]
- GSE287884 Targeted citrullination enables p53 binding to non-canonical sites [168] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE287872 Targeted citrullination enables p53 binding to non-canonical sites [166] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE287889 Targeted citrullination enables p53 binding to non-canonical sites [179] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE287887 Targeted citrullination enables p53 binding to non-canonical sites [178] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE288341 Targeted citrullination enables p53 binding to non-canonical sites [180] January 17, 2026Contributors : Alexandra Indeglia ; Andrea Valdespino ; Giulia Pantella ; Sarah Offley ; Connor Hill ; Alessandro Gardini ; Maureen E MurphySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTP53 encodes for the transcription factor p53, which binds to a diverse set of target genes in response to stress. Acti […]
- GSE288344 Targeted citrullination enables p53 binding to non-canonical sites January 17, 2026Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE292005 Direct reprogramming of human dermal fibroblasts into functional osteoblasts using cell-permeable Oct4-30Kc19 and Cbfβ-30Kc19 January 17, 2026Contributors : Manho Kim ; Jaeyoung Lee ; Wijin Kim ; Songrae Kim ; Ju Hyun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to induce the direct reprogramming of human dermal fibroblasts (HDFs) into osteoblast-like cells using the recombinant fusion proteins Oct4-30Kc19 and Cbfβ-30Kc19. Oct4 is a tr […]
- GSE316223 An In Vivo Model of a-Synuclein Spread from Gut to Brain January 17, 2026Contributors : Lisa M. Barnhill ; Sataree Khuansuwan ; Wael El Nachef ; Sung Min Ha ; Marisol Arellano ; Kazi Md Mahmudul Hasan ; Aaron Kim ; Jeff M. BronsteinSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioBackground: Parkinson’s disease is a progressive neurodegenerative disorder characterized by the presence of pathol […]