Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE300155 ERG preserves endothelial identity to limit atherosclerosis June 10, 2026Contributors : Steven R Botts ; Jason E Fish ; Kathryn L HoweSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEndothelial function is a critical safeguard against atherosclerosis. At atheroprone sites, the normally protective arterial endothelium can undergo endothelial-to-mesenchymal transition (EndMT), but the timing, […]
- GSE299601 DUX4 activates a transcriptional network involving Krüppel-like factors KLF17 and KLF18 [ChIP-Seq] June 10, 2026Contributors : Danielle C. Hamm ; Aidan B. O’Donnell ; Sean R. Bennett ; Richard J. L. F. Lemmers ; Patrick J. van der Vliet ; Silvère M. van der Maarel ; Stephen J. TapscottSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensSean, R. Bennett
- GSE240411 Identification of potential targets of FTO in GIST via transcriptome-wide RNA-seq June 10, 2026Contributors : Zhi Li ; Junju He ; Lunquan SunSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTyrosine kinase inhibitor (TKIs) resistance remains the leading obstacle for treating gastrointestinal stromal tumor (GIST), in which the secondary mutations within KIT causes escape of TKI inhibition and KIT reactivation. Here […]
- GSE302210 Extracellular Vesicle Online Knowledge Explorer (EVOKE) - A guiding tool for the selection of methods to prepare extracellular vesicles from human biofluids I June 10, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensExtracellular vesicles (EVs) exert multiple biological functions which has spurred their development as disease biomarkers and drug delivery vehicles. However, the wide range of EV preparation methods and the complexity of biofluids pose significant challenges for reproduc […]
- GSE292291 Loss of Ambp ameliorates MASLD progression via generating protective ROS and activating PPAR signaling pathway June 10, 2026Contributors : Lei Zhou ; Mei Wu ; Xiaoyu Li ; Jingjing ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioBackground: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a widespread and severe hepatic disease, affecting approximately 30% of the global population. Despite its prevalence, the precise pa […]
- GSE269555 Targeting the oncohistone-ASCL1 axis disrupts plasticity and suppresses pediatric gliomas [CUT&RUN] June 10, 2026Contributors : Alan Jiao ; Yang ShiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensPhenotypic plasticity, a hallmark of cancer facilitated by epigenomic reprogramming, represents a significant challenge but also therapeutic opportunity for cancer treatment. How plasticity is regulated in diffuse midline gl […]
- GSE334320 Selective insertion of a payload into NK cell checkpoint NKG2A, as a new platform for treating AML. June 10, 2026Contributors : Asuncion Borrero Borrego ; Saar Gill ; Maksim ShestovSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNatural killer (NK) cells are promising effectors for immunotherapy due to their intrinsic ability to recognize and eliminate malignant cells without prior sensitization. In acute myeloid leukaemia (AML), […]
- GSE292607 Clonal analysis and transcriptional profiling of ex vivo expanded mobilized peripheral blood hematopoietic stem and progenitor June 10, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE334495 Transcriptome data of miR-30e-5p overexpression in human aortic endothelial cells June 10, 2026Contributors : Chen Wang ; Jianqing She ; John Shyy ; Zu-yi YuanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo explore the transcriptional changes in human aortic endothelial cells (HAECs) caused by miR-30e-5p overexpression, we transfected HAECs with miR-30e-5p mimics or control miRNA and profiled transcriptomes by […]
- GSE334412 Brain corticogenesis promotes SARS-CoV-2 neuro-glial tropism through lipid-dependent viral replication June 10, 2026Contributors : Nhu Mai Thi Quynh ; Jieun Park ; Byoung-San MoonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHuman induced pluripotent stem cell (hIPSC)-derived cerebral organoids (CBOs) provide a potential in-vitro model to study cellular composition and transcriptional dynamics during human brain development. This s […]
- GSE334521 Atlas of tissue-specific and tissue-preferential gene expression in ecologically and economically significant conifer Pinus sylvestris June 10, 2026Contributors : Ojeda I Dario ; Cervantes Sandra ; Ruttink Tom ; Kujala T Sonja ; Kärkkäinen Katri ; Verta Jukka-Pekka ; Cervantes Sandra ; Vuosku Jaana ; Mattila M Tiina ; Pyhäjärvi TanjaSeries Type : Expression profiling by high throughput sequencingOrganism : Pinus sylvestrisWe provide an atlas of gene expression patterns for conifer Pinus sylvestris acros […]
- GSE334603 Bacteroides Fragilis enterotoxin engagement of the colonic epithelium is associated with early YAP1 activation and colon tumorigenesis June 10, 2026Contributors : Franck Housseau ; Nile Liu ; Ada TamSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEnterotoxigenic Bacteroides fragilis (ETBF) promotes colonic inflammation and tumorigenesis, but the epithelial signaling events linking toxin (BFT2)-induced junctional injury to tumor development remain incompletely defin […]
- GSE334629 RelB Drives Integrin-Mediated Stress Tolerance and Relapse in High-Grade Serous Ovarian Cancer June 10, 2026Contributors : Mikella Robinson ; Omar Lujano-Olazaba ; Nathan Wong ; Carrie HouseSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHigh-grade serous ovarian cancer (HGSOC) often relapses after chemotherapy due to chemoresistant cancer stem-like cells (CSCs). NF-κB signaling, previously shown to enhance stemness traits, w […]
- GSE299395 RNA-seq of B-cell lymphoma treated with Ibrutinib and CAR T cells June 10, 2026Contributors : Yi-Lin Chiu ; Xin-Jie Lu ; Hsing-Fan LaiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis dataset presents RNA sequencing (RNA-seq) data from human B-cell lymphoma HT tumors established in immunodeficient mice. Tumors were treated with ibrutinib (IB), CD19-directed chimeric antigen receptor T cells (CA […]
- GSE334271 In vivo base editing partially rescues bone dysplasia in a mouse model of Hutchinson-Gilford Progeria Syndrome June 10, 2026Contributors : Wayne A Cabral ; Caleb M Grenko ; Diana Yeritsyan ; Indeevar Beeram ; Shubham Laiwala ; Lukas R Johnson ; Urraca L Tavarez ; Tingfen Yan ; Stephen M Wincovitch ; Luke W Koblan ; Xin D Gao ; Meirui An ; Narisu Narisu ; Leslie G Biesecker ; David R Liu ; Ara Nazarian ; Francis S Collins ; Michael R ErdosSeries Type : Expression profiling by high […]