Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE304561 Heterogeneity in B- and epithelial-cell senescence in the pathogenesis of COPD/emphysema [scRNA-seq] August 9, 2026
  Contributors : Gagandeep Kaur ; Qixin Wang ; Felix Effah ; Sadiya Bi Shaikh ; Calla Fahey ; Ariel Tjitropronoto ; Hoshang Unwalla ; Manoj Mammen ; Irfan RahmanSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensIncreased cellular senescence leading to premature lung aging is a key mechanism for chronic inflammation […]
• GSE275198 Exploring transcriptomic change in CM-Leukemia August 9, 2026
  Contributors : Lianjun Zhang ; Yu-Hsuan Fu ; Ya-Huei KuoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo explore the transcriptome change in CM-leukemia, we performed RNA-seq for bone marrow mononuclear cells from CM mice at the leukemic stage and control littermate.
• GSE317372 Stroma-oriented tumor microenvironment facilitates intraosseous ameloblastoma tumor growth [RNA-Seq] August 9, 2026
  Contributors : Da-Yo Yuh ; Ting-Han ChangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAmeloblastoma is a locally aggressive odontogenic epithelial tumor with poorly understood intraosseous pathogenesis due to a lack of physiologically relevant models. Here, we established an orthotopic intraosseous mouse model using […]
• GSE306322 Single cell multiomic profiling of heterogenous PROCR+ cells in mouse mammary gland [scATAC-Seq] August 9, 2026
  Contributors : Erin Nekritz ; Koon-Kiu Yan ; Jiyang Yu ; Jose SilvaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPROCR has been identified as a surface marker on cyclic mammary stem cells (MaSCs) in the basal layer of the mouse mammary gland. Due to their limited numbers, this population has not been cle […]
• GSE250034 Steroid receptor crosstalk in granulosa cells during ovulation August 9, 2026
  Series Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
• GSE317374 Stroma-oriented tumor microenvironment facilitates intraosseous ameloblastoma tumor growth [multiome] August 9, 2026
  Contributors : Da-Yo Yuh ; Jian-Liang Chou ; Ting-Han ChangSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensAmeloblastoma is a locally aggressive odontogenic epithelial tumor with poorly understood intraosseous pathogenesis due to a lack of physiologicall […]
• GSE337141 Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming [CRISPRscreen] August 9, 2026
  Contributors : Arik Toren ; Liron Hoffman ; Irina Miodownik ; Yoav Mayshar ; Raz Ben-Yair ; Ayelet-Hashahar Orenbuch ; Hernan Rubinstein ; Aviezer Lifshitz ; Roni Stok Ranen ; Alexander Wainstein ; Daoud Sheban ; Liran Shlush ; Amos Tanay ; Ariel Afek ; Yonatan StelzerSeries Type : OtherOrganism : Mus musculusGenomic imprinting secures parent-specific gene e […]
• GSE260472 Kidney collecting duct cell type composition is regulated by Notch signaling via modulation of mTORC1 activity (ChIP-Seq) August 9, 2026
  Contributors : Kameswaran Surendran ; Michael KaretaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThe kidneys play an essential role in water and electrolyte homeostasis that is dependent on maintenance of intermingled epithelial cell types within tubular collecting duct segments. Notch signaling, a regu […]
• GSE337302 Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming [bulk RNAseq] August 9, 2026
  Contributors : Arik Toren ; Liron Hoffman ; Irina Miodownik ; Yoav Mayshar ; Raz Ben-Yair ; Ayelet-Hashahar Orenbuch ; Hernan Rubinstein ; Aviezer Lifshitz ; Roni Stok Ranen ; Alexander Wainstein ; Daoud Sheban ; Liran Shlush ; Amos Tanay ; Ariel Afek ; Yonatan StelzerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGeno […]
• GSE337143 Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming [ChIP-seq] August 9, 2026
  Contributors : Arik Toren ; Liron Hoffman ; Irina Miodownik ; Yoav Mayshar ; Raz Ben-Yair ; Ayelet-Hashahar Orenbuch ; Hernan Rubinstein ; Aviezer Lifshitz ; Roni Stok Ranen ; Alexander Wainstein ; Daoud Sheban ; Liran Shlush ; Amos Tanay ; Ariel Afek ; Yonatan StelzerSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mu […]
• GSE337303 Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming [CUT&Tag] August 9, 2026
  Contributors : Arik Toren ; Liron Hoffman ; Irina Miodownik ; Yoav Mayshar ; Raz Ben-Yair ; Ayelet-Hashahar Orenbuch ; Hernan Rubinstein ; Aviezer Lifshitz ; Roni Stok Ranen ; Alexander Wainstein ; Daoud Sheban ; Liran Shlush ; Amos Tanay ; Ariel Afek ; Yonatan StelzerSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mu […]
• GSE342353 A Nanomolar-Affinity Antibody Enabling Sensitive Labeling and High-Resolution Genomic Mapping of O-GlcNAc August 9, 2026
  Contributors : Weiyao Hong ; Che Zhang ; Xiaoyang GuoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusHigh-affinity O-GlcNAc-specific antibodies are crucial for the sensitive detection and functional study of O‑GlcNAcylation. Here, we report the development of a pan-specific, nanomolar-affinity O-GlcNAc ant […]
• GSE342412 Global regulatory role of stringent starvation protein SspA in modulating IncX3 plasmid fitness cost in Escherichia coli August 9, 2026
  Contributors : Ziyi Liu ; Ying Tang ; Chenggang XuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Escherichia coliThe IncX3 plasmid is a primary vector for disseminating carbapenem resistance globally, yet the chromosomal regulatory mechanisms governing its fitness cost remain poorly understood. Our previous work iden […]
• GSE274441 RNA-seq for CMK and M07E cell line in either the absence or presence of GNE987 August 9, 2026
  Contributors : Fang Fang ; Jian Pan ; Ailian Guo ; Zhiheng LiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNext-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare RNA-seq results for CMK and M07E cell line in either the absence or presence […]
• GSE337139 Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming [Bisulfite] August 9, 2026
  Contributors : Arik Toren ; Liron Hoffman ; Irina Miodownik ; Yoav Mayshar ; Raz Ben-Yair ; Ayelet-Hashahar Orenbuch ; Hernan Rubinstein ; Aviezer Lifshitz ; Roni Stok Ranen ; Alexander Wainstein ; Daoud Sheban ; Liran Shlush ; Amos Tanay ; Ariel Afek ; Yonatan StelzerSeries Type : Methylation profiling by high throughput sequencingOrganism : Mus musculusGen […]