Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE310366 Targeted Elimination of FAP⁺ Fibroblasts by BiTE-Engineered Extracellular Vesicles Prevents Epidural Fibrosis June 7, 2026
  Contributors : Zheng Zhang ; Wei Xiong ; Liang Huang ; Shanwei Ye ; Qian XuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEpidural fibrosis (EF) is a frequent and debilitating complication that impairs recovery following spinal surgery, yet effective targeted therapies are lacking. Here we observe enrichment of FAP⁺ fi […]
• GSE299535 Gene expression analysis of early Barrett's adenocarcinoma, Barrett's esophagus, normal gastric mucosa, and esophageal mucosa June 7, 2026
  Contributors : Dai Kubota ; Yu TakahashiSeries Type : Expression profiling by arrayOrganism : Homo sapiensThe objective of this study was to identify genes and pathways early Barrett's adenocarcinoma through comprehensive gene expression analysis.
• GSE316842 Transcriptomic Profiling of Blood-Stage Plasmodium falciparum in Children with Severe Malarial Anemia June 7, 2026
  Contributors : Douglas J Perkins ; Qiuying Cheng ; Ivy Hurwitz ; Christophe G Lambert ; Philip D Seidenberg ; Kristan A Schneider ; Benjamin H McMahon ; Collins Ouma ; Evans Raballah ; Samuel B Anyona ; Clinton O Onyango ; Anne A Ong'ondo ; Nicholas O Ondiek ; Everlyne Modi ; Joan A Ochieng ; Vincent I Omanje ; Rodney B Mongare ; Sharley A Wasena ; Sham […]
• GSE310989 Bispecific Antibody Engineered Extracellular Vesicles Redirect T Cells to Prevent Postoperative Epidural Fibrosis [scRNA-seq] June 7, 2026
  Contributors : Zheng Zhang ; Wei Xiong ; Liang Huang ; Shanwei Ye ; Qian XuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEpidural fibrosis (EF) is a frequent and debilitating complication that impairs recovery following spinal surgery, yet effective targeted therapies are lacking. Here we observe enrichment of FAP⁺ fi […]
• GSE255645 RNA-sequencing results of the human thyroid papillary carcinoma cell TPC-1 with overexpression of the PTCSC3-AS1 gene June 7, 2026
  Contributors : Yanqiang Wang ; Yutong ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHere we report gene expression profiles of TPC-1 cells treated with PTCSC3-AS1 overexpressed vector (OE) or empty vector (EV). PTCSC3-AS1 gene was cloned from expressed sequence tag (AA632637). And the sequence of PTCSC3-AS1 is in […]
• GSE334479 Whole-genome bisulfite sequencing reveals dynamic DNA methylation changes in Vigna radiata under direct and pre-conditioned salt stress June 7, 2026
  Series Type : Methylation profiling by high throughput sequencingOrganism : Vigna radiataDNA methylation is an important epigenetic mechanism regulating gene expression and stress memory in plants. To investigate the role of DNA methylation in salt stress adaptation, we performed whole-genome bisulfite sequencing (WGBS) of mung bean (Vigna radiata cv. Weilv […]
• GSE333968 Vitamin B6 Promotes Endoderm Differentiation of Mouse Embryonic Stem Cells via Glycolysis-H3K18 Lactylation Axis June 7, 2026
  Contributor : Dengwang ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusVitamin B6 (pyridoxine) is widely used as a first-line treatment for nausea and vomiting during pregnancy, yet its safety profile during embryonic development, particularly at supraphysiological doses, remains incompletely understood.
• GSE269386 Oxidative and glycolytic skeletal muscle-derived exosomes selectively coated miRNAs and participate in regulating myoblast proliferation and differentiation mediated by miR-4331-3p June 7, 2026
  Contributors : Jia Luo ; Daiyu Zhang ; Zhenhao Wen ; Qiang Pu ; Taorun Luo ; Xiaoqian Wu ; Jie Chai ; Li Chen ; Changfeng Yang ; Yongfu HuangSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Sus scrofaThe phenotypic characteristics and meat quality of skeletal muscle are collectively determined by the muscle cells, other cellular […]
• GSE334034 Targeting mitochondrial ROS-CK2-SET-PP2A pathway with ceria nanoparticles to reverse Tau pathology in APOEε4-associated Alzheimer’s disease [RNA-seq] June 7, 2026
  Contributors : Jong Won Han ; Yubeen Kim ; June-Hyun Jeong ; Yunjung Lee ; Dakyung Lee ; Suk-Kyung Shin ; Seok Beom Hong ; Keuntae Kim ; Sieun Choi ; Rian Kang ; Jong-Chan Park ; Kangmin Suh ; Jinyoung Chu ; Nohyun Lee ; Sang Ihn Han ; Dong-Sup Lee ; Il-Joo Cho ; Seok Chung ; Jong-Il Kim ; Taeghwan Hyeon ; Inhee Mook-JungSeries Type : Expression profiling by […]
• GSE334026 CUT&Tag of H3K18 lactylation in mouse embryonic stem cells treated with vitamin B6 for 7 days June 7, 2026
  Contributor : Dengwang ChenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusVitamin B6 (pyridoxine) is widely used as a first-line treatment for nausea and vomiting during pregnancy, yet its safety profile during embryonic development, particularly at supraphysiological doses, remains incompletely understoo […]
• GSE334035 Targeting mitochondrial ROS-CK2-SET-PP2A pathway with ceria nanoparticles to reverse Tau pathology in APOEε4-associated Alzheimer’s disease [scRNA-seq] June 7, 2026
  Contributors : Jong Won Han ; Yubeen Kim ; June-Hyun Jeong ; Yunjung Lee ; Dakyung Lee ; Suk-Kyung Shin ; Seok Beom Hong ; Keuntae Kim ; Sieun Choi ; Rian Kang ; Jong-Chan Park ; Kangmin Suh ; Jinyoung Chu ; Nohyun Lee ; Sang Ihn Han ; Dong-Sup Lee ; Il-Joo Cho ; Seok Chung ; Jong-Il Kim ; Taeghwan Hyeon ; Inhee Mook-JungSeries Type : Expression profiling by […]
• GSE334477 Transcriptome analysis of Vigna radiata leaves in response to direct and pre-conditioned salt stress [RNA-Seq] June 7, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Vigna radiataWe investigated the adaptive responses of mung bean cultivar 'Weilv 9' to salt stress using RNA-seq. Two treatments were applied: T1 (pre-conditioned with 100 mM NaCl for 24 h, recovered for 48 h, then re-exposed to 100 mM NaCl) and T2 (direct exposure to 100 mM […]
• GSE334478 ATAC-seq profiling of chromatin accessibility in Vigna radiata leaves under direct and pre‑conditioned salt stress June 7, 2026
  Series Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Vigna radiataSalinity is a major environmental constraint limiting crop productivity. Chromatin accessibility plays a crucial role in transcriptional regulation under stress conditions. In this study, we investigated genome-wide chromatin accessibility dynamics in mung b […]
• GSE299273 Relationship between environmental pollutant TBOEP and renal metabolism June 7, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTris(2-butoxyethyl) phosphate (TBOEP) is a common organophosphorus compound widely used in industrial production as a plasticizer and flame retardant. In recent years, studies have shown that TBOEP may pose potential threats to human health, particularly its association wi […]
• GSE333543 The lateral septum orchestrates state-dependent modulation of associative threat memory dynamics across the ovarian hormone cycle June 7, 2026
  Contributor : Elizabeth K LucasSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSingle-nucleus ATAC- and RNA-sequencing data from adult female proestrus C57Bl/6J mouse brain lateral septum, threat conditioned and naive control animals. This GEO submission contains the processed RNA-seq/single-nucleus RNA-seq data associa […]