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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE297108 Mapping genetic modifiers of epimutation rates identifies VIM2/4 as dosage-sensitive negative regulators of CG methylation maintenance July 18, 2026Series Type : Methylation profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaThis SuperSeries is composed of the SubSeries listed below.
- GSE297077 Mapping genetic modifiers of epimutation rates identifies VIM2/4 as dosage-sensitive negative regulators of CG methylation maintenance [ATAC-seq] July 18, 2026Contributors : Zhilin Zhang ; Wilma Wanney ; Robert J Schmitz ; Frank JohannesSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Arabidopsis thalianaSpontaneous epimutations—stochastic changes in cytosine methylation—can persist across generations in plants and are thought to contribute to phenotypic variation. Although […]
- GSE303260 SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors [MSC_hTERT] July 18, 2026Contributors : Pirson Constance ; Sablon Ariane ; Loriot Axelle ; Demoulin Jean-BaptisteSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSRF fusion genes result from chromosomal translocations in muscle-related soft tissue tumors, including perivascular tumors, myofibroma and rhabdomyosarcoma. SRF encodes the Serum Respo […]
- GSE303259 SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors [C2C12] July 18, 2026Contributors : Pirson Constance ; Sablon Ariane ; Loriot Axelle ; Demoulin Jean-BaptisteSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSRF fusion genes result from chromosomal translocations in muscle-related soft tissue tumors, including perivascular tumors, myofibroma and rhabdomyosarcoma. SRF encodes the Serum Respo […]
- GSE338555 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [TGFB_scRNAseq] July 18, 2026Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]
- GSE333187 Cystine Restriction Alleviates T Cell Exhaustion and Enhances CAR-T Cell Potency July 18, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis study was designed to explore how targeting Slc7a11 affected CD8+ T cell differentiation and function using a mouse colorectal cancer model. Single-cell RNA-seq was used to monitor tumor-infiltrating CD8+ T cells from Slc7a11 knockout and wild-type mouse tumor models […]
- GSE333206 Mapping genetic modifiers of epimutation rates identifies VIM2/4 as dosage-sensitive negative regulators of CG methylation maintenance [RNAseq_VIM2/4] July 18, 2026Contributors : Zhilin Zhang ; Wilma Wanney ; Frank Johannes ; Yangyang Xu ; Robert J SchmitzSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaSpontaneous epimutations are stochastic gains and losses of cytosine methylation that arise from imperfect maintenance across cell divisions. At CG sites, such epimutations […]
- GSE287465 Targeting DDR2 for Treating Pancreatic Cancer July 18, 2026Contributors : Chris TP Do ; Pitta Prabhakar ; Jack Y. Prochnau ; Deepika Singh ; Santosh Timilsina ; Panneerdoss Subbarayalu ; Daisy Medina ; Shahad Abdulsahib ; Saif Nirzhor ; Sajid Khan ; Guiming Li ; Srikanth Polusani ; Daohong Zhou ; Pei Wang ; Zhao Lai ; Yidong Chen ; Ratna K. Vadlamudi ; Mathew Hart ; Radhika Amaradhi ; Stanton McHardy ; Manjeet K. Ra […]
- GSE338411 Transcriptomic changes in the mouse olfactory bulb following peripheral SARS-CoV-2 infection July 18, 2026Contributors : Abhishek K Verma ; Lu Tan ; Stanley PerlmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNeuroinflammation and microglial activation in the olfactory bulb have been reported in animal models of SARS-CoV-2 infection. This study aims to characterize the neuronal transcriptional changes associated with the […]
- GSE337966 Benchmarking CUT&RUN analysis procedure using motif enrichment July 18, 2026Contributors : Luomeng Tan ; Coby Viner ; Xing Hao Li ; Michael M Wrana ; Charles A Ishak ; Shu Yi Shen ; Daniel D De Carvalho ; Sarah J Hainer ; Michael M HoffmanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensWe designed a benchmarking method to evaluate peak calling procedures for CUT&RUN data and t […]
- GSE338421 Identification of the Molecular Targets Underlying the Anticancer Effects of Betulonic Acid, One of the Active Constituents of Celastrus orbiculatus, in Gastric Cancer Cells July 18, 2026Contributors : Zewen Chu ; Yue Ding ; Yanwei XiangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the potential targets, related signaling pathways, and molecular mechanisms of betulonic acid, one of the active constituents of Celastrus orbiculatus, in gastric cancer cells, reference-based transcriptome s […]
- GSE338553 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [Full_Low_Serum] July 18, 2026Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]
- GSE338554 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [TGFB_bulkRNAseq] July 18, 2026Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]
- GSE296957 Mapping genetic modifiers of epimutation rates identifies VIM2/4 as dosage-sensitive negative regulators of CG methylation maintenance [WGBS] July 18, 2026Contributors : Zhilin Zhang ; Robert J Schmitz ; Frank JohannesSeries Type : Methylation profiling by high throughput sequencingOrganism : Arabidopsis thalianaSpontaneous epimutations—stochastic changes in cytosine methylation—can persist across generations in plants and are thought to contribute to phenotypic variation. Although epimutations are increasingl […]
- GSE333205 Mapping genetic modifiers of epimutation rates identifies VIM2/4 as dosage-sensitive negative regulators of CG methylation maintenance [WGBS_VIM2/4] July 18, 2026Contributors : Zhilin Zhang ; Wilma Wanney ; Frank JohannesSeries Type : Methylation profiling by high throughput sequencingOrganism : Arabidopsis thalianaSpontaneous epimutations are stochastic gains and losses of cytosine methylation that arise from imperfect maintenance across cell divisions. At CG sites, such epimutations can be inherited across generati […]