Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE287465 Targeting DDR2 for Treating Pancreatic Cancer July 18, 2026
  Contributors : Chris TP Do ; Pitta Prabhakar ; Jack Y. Prochnau ; Deepika Singh ; Santosh Timilsina ; Panneerdoss Subbarayalu ; Daisy Medina ; Shahad Abdulsahib ; Saif Nirzhor ; Sajid Khan ; Guiming Li ; Srikanth Polusani ; Daohong Zhou ; Pei Wang ; Zhao Lai ; Yidong Chen ; Ratna K. Vadlamudi ; Mathew Hart ; Radhika Amaradhi ; Stanton McHardy ; Manjeet K. Ra […]
• GSE272618 Single-Molecule Barcoding Technology for Single-Cell Genomics July 18, 2026
  Contributors : Ivan Garcia-Bassets ; Yu XiaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusRecent advances in barcoding technologies have introduced unprecedented scalability to single-cell genomic experiments. However, most large-scale studies are focused on the generation of reference cell atlases, whic […]
• GSE303259 SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors [C2C12] July 18, 2026
  Contributors : Pirson Constance ; Sablon Ariane ; Loriot Axelle ; Demoulin Jean-BaptisteSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSRF fusion genes result from chromosomal translocations in muscle-related soft tissue tumors, including perivascular tumors, myofibroma and rhabdomyosarcoma. SRF encodes the Serum Respo […]
• GSE293743 Expression data from human dermal papilla cells July 18, 2026
  Contributors : Ryo Takahashi ; Masahiro Fukuyama ; Aki Tsukashima ; Momoko Kimishima ; Yoshimi Yamazaki ; Manabu OhyamaSeries Type : Expression profiling by arrayOrganism : Homo sapiensDermal papilla is pivotal for hair follicle morphogenesis and regeneration. However, isolation of human DP cells still depends on laborious microdissection and in vitro expans […]
• GSE333187 Cystine Restriction Alleviates T Cell Exhaustion and Enhances CAR-T Cell Potency July 18, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis study was designed to explore how targeting Slc7a11 affected CD8+ T cell differentiation and function using a mouse colorectal cancer model. Single-cell RNA-seq was used to monitor tumor-infiltrating CD8+ T cells from Slc7a11 knockout and wild-type mouse tumor models […]
• GSE303260 SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors [MSC_hTERT] July 18, 2026
  Contributors : Pirson Constance ; Sablon Ariane ; Loriot Axelle ; Demoulin Jean-BaptisteSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSRF fusion genes result from chromosomal translocations in muscle-related soft tissue tumors, including perivascular tumors, myofibroma and rhabdomyosarcoma. SRF encodes the Serum Respo […]
• GSE337966 Benchmarking CUT&RUN analysis procedure using motif enrichment July 18, 2026
  Contributors : Luomeng Tan ; Coby Viner ; Xing Hao Li ; Michael M Wrana ; Charles A Ishak ; Shu Yi Shen ; Daniel D De Carvalho ; Sarah J Hainer ; Michael M HoffmanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensWe designed a benchmarking method to evaluate peak calling procedures for CUT&RUN data and t […]
• GSE333188 Cystine Restriction Alleviates T Cell Exhaustion and Enhances CAR-T Cell Potency July 18, 2026
  Series Type : OtherOrganism : Mus musculusThis study was designed to explore how targeting Slc7a11 affected CD8+ T cell differentiation and function using a mouse colorectal cancer model. TCR-seq was used to profile T cell receptor repertoires in mouse tumor-infiltrating T cells from wild-type and Slc7a11 knockout tumor models treated with IgG control or ant […]
• GSE338411 Transcriptomic changes in the mouse olfactory bulb following peripheral SARS-CoV-2 infection July 18, 2026
  Contributors : Abhishek K Verma ; Lu Tan ; Stanley PerlmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNeuroinflammation and microglial activation in the olfactory bulb have been reported in animal models of SARS-CoV-2 infection. This study aims to characterize the neuronal transcriptional changes associated with the […]
• GSE338421 Identification of the Molecular Targets Underlying the Anticancer Effects of Betulonic Acid, One of the Active Constituents of Celastrus orbiculatus, in Gastric Cancer Cells July 18, 2026
  Contributors : Zewen Chu ; Yue Ding ; Yanwei XiangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the potential targets, related signaling pathways, and molecular mechanisms of betulonic acid, one of the active constituents of Celastrus orbiculatus, in gastric cancer cells, reference-based transcriptome s […]
• GSE338553 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [Full_Low_Serum] July 18, 2026
  Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]
• GSE338554 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [TGFB_bulkRNAseq] July 18, 2026
  Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]
• GSE338555 Endothelial-to-mesenchymal transition in tumor mesenchymal stem cells elicits pro-tumorigenic IL-11+ cancer-associated myofibroblasts [TGFB_scRNAseq] July 18, 2026
  Contributors : Giorgia B Pisoni ; Shoko Kure ; Saba Tabasum ; Michael P Manos ; Ian D Dryg ; Robert Gentleman ; Joanna Baginska ; Julia Huezo ; Scott Ficarro ; Farzaneh Kordbacheh ; Geoffrey G Fell ; Srinika Ranasinghe ; Jason L Weirather ; Anita Giobbie-Hurder ; F S HodiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensT […]